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![]() Now and then, you can look away and then resume the conversation usually, but it is vital to be present entirely when someone is speaking to you. Maintaining eye contact does not mean you must constantly stare at the speaker. Therefore, facing the speaker and maintaining eye contact is essential for effective listening skills. Listening to a person while working on a computer screen or scanning the room will only give the speaker a certain percentage of your divided attention. It would help if you prepared yourself to listen. At home, effective listening skills help develop children who are self-reliant and resourceful and can solve their problems. Listening has become so crucial in organizations today that several top employers are providing training in effective listening skills to their employees as they are aware that effective listening skills facilitate better satisfaction to the consumers, increase productivity in the workplace, assure adequate information sharing, lead to more innovative and creative work, lesser errors and less wastage of time. If you listen carefully, the communication process will stay smooth despite the misunderstandings, making the sender feel satisfied. Concentrating along with using other senses is a practical listening skill. The ability to accurately receive and interpret messages during communication is known as listening. Listening skills hold the key to effective communication. Updated JIntroduction to Effective Listening Skills ![]() HCT from alternative donors is typically undertaken only in patients with severe symptoms, causing or likely to cause organ damage, and in the context of clinical trials. In young children with symptomatic SCD with an available HLA-identical related donor, HCT should be carefully considered. Presented at: Society of Hematologic Oncology 2023 Annual Meeting September 6-9, 2023 Houston, TX.Excellent outcomes in hematopoietic cell transplantation (HCT) from HLA-identical siblings, improvements in conditioning regimens, novel graft-versus-host disease prophylaxis, and the availability of alternative donors have all contributed to the increased applicability and acceptability of HCT for sickle cell disease (SCD). Impact of consolidation chemotherapy intensity before allogeneic hematopoietic stem cell transplantation in elderly patients with acute myeloid leukemia. Additionally, nonmyeloablative haploidentical stem cell transplant with peripheral blood cells and post-transplant cyclophosphamide has allowed for long-term survival in elderly patients with AML or myelodysplastic syndrome.įurther research is ongoing, including a phase 2 study that will compare venetoclax plus cytarabine to idarubicin and cytarabine as maintenance therapy in elderly AML patients in CR1. The development of new drugs and treatment approaches, such as FLT3 inhibitors, CPX-351, IDH inhibitors, and venetoclax followed by stem cell transplant, have improved the landscape of AML therapeutics. In conclusion, the study showed that there is no impact of intensive versus non-intensive consolidation chemotherapy before HSCT in elderly AML patients over 60 in CR1. There was also no difference in the rate of graft-versus-host disease based on the consolidation regimen. Unfavorable cytogenetic risk was associated with worse RFS. The study revealed no significant difference in overall survival between the two cohorts, with 2-year rates of 52% for intensive therapy and 58% for non-intensive therapy (P =. The baseline characteristics of the patients were comparable between the two groups. Of these, 68 patients received non-intensive therapy consisting of low-dose cytarabine or azacytidine, and 62 patients received intermediate- or high-dose cytarabine. The analysis included 130 patients over the age of 60 in CR1 who underwent allogeneic HSCT. The study aimed to address conflicting data on the benefit of intensive versus non-intensive consolidation in the elderly population by conducting a retrospective analysis over a 10-year period. Yosr Hicheri highlighted the limitations of the study, including missing molecular data in some patients, the absence of measurable residual disease, and a lack of detailed analysis of post-transplant complications. 564), although this difference was not statistically significant. However, there was a trend towards worse NRM with intensive therapy, possibly due to complications such as infections, with a 2-year rate of 27% compared to 16% with non-intensive treatment (P =. The study found that both regimens had similar relapse-free survival (RFS) and non-relapse mortality (NRM) rates.Īt a median follow-up of 52.2 months, the 2-year RFS rate was 51% for patients who received intensive therapy and 50% for those who received non-intensive therapy, indicating no significant difference in outcomes (P =. A retrospective analysis presented at the 2023 Society of Hematologic Oncology Annual Meeting compared the outcomes of intensive and non-intensive consolidation chemotherapy regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients over 60 with acute myeloid leukemia (AML) in first complete remission (CR1). ![]() System Requirements for CCleaner Professional with Portable and MacOSīefore you install CCleaner Professional with Portable and MacOS Free Download you need to know if your pc meets recommended or minimum system requirements:ĬCleaner Professional with Portable and MacOS Technical Setup Details By overwriting the files before deleting them, making it impossible to recover the data. For the super cautious users we also offer secure file erasing.We also certify that it contains no Spyware or Adware. ![]() It has multiple levels of checks in place to ensure that it cannot delete any useful information or documents you may still need. CCleaner was designed from the ground to be safe and secure to use.CCleaner uses an advanced Registry Cleaner to check for problems and inconsistencies.Including: Firefox, Opera, Safari, Media Player, eMule, Kazaa, Google Toolbar, Netscape, Microsoft Office, Nero, Adobe Acrobat Reader, WinRAR, WinAce, WinZip and more As well as cleaning up old files and settings left by standard Windows components, CCleaner also cleans temporary files and recent file lists for many applications.You also may like to download Notepad++ 7.6.4 with Porable.įeatures of CCleaner Professional with Portable and MacOSīelow are some amazing features you can experience after installation of CCleaner Professional with Portable and MacOS Free Download please keep in mind features may vary and totally depends if your system support them. Aside from the last one, which deals with application settings, each of the other three perform different jobs in various areas of your machine. You can also download FontExpert 2019 with Portable.ĬCleaner features a clean, professional-looking interface split into four areas: Cleaner, Registry, Tools and Options. ![]() It performs an in-depth analysis of almost all areas of your system and detects unused or invalid entries that clog the Windows registry, preventing it from running at its best. CCleaner Professional with Portable and MacOS OverviewĬCleaner deals with a rather sensitive segment involved in computer maintenance, namely secure cleaning. Program was checked and installed manually before uploading by our staff, it is fully working version without any problems. It is full offline installer standalone setup of CCleaner Professional with Portable and MacOS Free Download for compatible version of windows. This is especially the case when that latest version of CCleaner has data collection options enabled by default (see the section below).CCleaner Professional with Portable and MacOS Free Download New and latest Version for Windows. It's a bit ironic to claim that going into a user's system without their permission and making changes is a move based on privacy and transparency. "Since the release of v5.46 we have updated some users to this version to meet legal requirements and give users more autonomy and transparency over their privacy settings." As it turned out, that's exactly what happened.Ī Piriform staff member responded with the following: A user on Piriform's forums noticed that CCleaner had automatically updated on his system without his permission. The latest CCleaner controversy comes from ignoring user preferences about checking for updates. In our opinion, it isn't time to trust CCleaner. This is unfortunately not surprising after Avast purchased CCleaner developer Piriform in July 2017. Why Is CCleaner No Longer Safe?ĬCleaner, once a tidy app with no history of issues, has had several major problems in less than a year. Here's why you can't trust CCleaner anymore, and what to replace it with. ![]() Remote update for NxClassifier ruleset disabled.Don't merge custom classified domains when it's not on Jahaslist.'HTTP_RECAT_MAX_LINE' has been increased to 100000.'IE Proxy Bypass' added on 'Policy > Proxy Filtering'.'is_queue_full' flag removed from MasterCheck.Not to share login session when master node down.'enable_auto_update' flag removed from NxClassifier.Remove respawn option from Systemd script.LDAP import excluded keyword size increased to 2,000 bytes.Not sending DNS response after caching bug from v3.3.0 fixed.UTF-8 support for Jahaslist remote repository text file.Removed redundancy checking for empty message from response cache.Cache DNS response only when it has at least one A record.Set 'false' for 'follow_referral' on LDAP login.Add auth_drop_cnt instead of auth_redi_cnt when authentication not enabled.Keep LDAP DN for an LDAP imported user for LDAP login.Remove duplicated username on the dropdown list on 'Report > Daily'.Send error message to NxClient when authentication disabled.Using standard DNS protocol for NxUpdate and NxClient signals and queries.Support for NxUpdate v1.x, NxClient v1.x stopped.New domain validation function applied for allowing the domains not having dot.LDAP importation bug in 'lete_user' fixed.Authoritative flag unset from block redirection.Bug for '172.16.x.x' with LibNet.is_private_ip method fixed.Remove protocol from reclassification request.MS DNS IP validation removed for adding secondary DNS IP on Active Directory importation setup.Block by window title has been removed from application control.Client password for remote filtering agent added.It features Active Directory and LDAP integration, group based policy assignment, block by domain categories, safe-search enforcing, dual policy setup for work-time and free-time, quota time, phishing Protection, application control, remote user filtering, unlimited custom categories, unlimited number of user and group creation, malware and botnet detection based on DNS packet inspection. You can filter and monitor Internet activity in your network on central GUI without latency problem. It combines lightweight DNS filter with local proxy filtering through its agent for the performance. NxFilter is a network level webfilter designed for enterprise environment. To even sweeten the deal, the program also allows the user to use any controller ideal for his or her hands. ![]() The application also has the fastest setting for PCSX2 plugins which also allows streamers and YouTubers to screen capture gameplay which will enable them to have a lot of creative freedom from games that run on the PlayStation 2. This has made it lightweight and easy to use. PCSX2 has become a successful emulator since the death of the PlayStation 2 since it emulates games through a set of mods which is done by modular programming. It began development in 2001 but was available in the July of 2006. Coming in with the ability to emulate any PlayStation 2 game, PCSX2 is very similar to its older compatriot, the fastest setting for PCSX2. PCSX2 is an open-source PlayStation 2 emulator that is free and is available on various platforms like Windows, Linux, and Mac OS. Making gamers or consumers who are looking for a nostalgic time booting up various emulators like PCSX2. To this very day, not a single console is as popular as the PlayStation 2. Sadly with the introduction of its successor, the PlayStation3, and the age of time taking its toll on it, the beloved PlayStation 2 was discontinued after thirteen years of production on January fourth, 2013. To sweeten the deal even more, Playstation 2 had support for a full 1080i high-definition gameplay, while other consoles couldn’t support such high-quality of gaming. This was a big step in the right direction to score more gamers and consumers, as the only way anyone could play online was through Xbox’s paid online service known as Xbox Live. Along with the passage of time, Sony even released a network adapter, which allowed the popular home console to access the internet for online multiplayer games for free. The PlayStation 2 dominated the market even after its successor, the PlayStation 3, was released. ![]() Boasting over three thousand eight hundred and seventy-four titles. It soon got the title of the best-selling video game console of all time shortly after the remodel. With it being sold like hotcakes, Sony refurbished the design to make the slimline models by 2004. It impressed the majority of the populace so much that it sold more than 154 million copies of the console. ![]() This made the consumers go crazy over it as it provided the pinnacle of gaming back in the day. Coming into the competition dominated by Microsoft’s Xbox and Nintendo’s Gamecube, it packed an impressive system RAM of 32 MB and a video RAM of 4 MB with a 64-bit emotion engine as CPU. ![]() This Agreement is made with such Lender in reliance upon such Lenders representation to the Borrower, which by its execution of this Agreement, it hereby confirms, that the Bridge Loan will be made for its own account, not as a nominee or agent, and not with a view to the resale or distribution of any part thereof, and that it has no present intention of selling, granting any participation in, or otherwise distributing the same. Such Lender has full power and authority to enter into this Agreement, and such Agreement constitutes such Lenders valid and legally binding obligation, enforceable in accordance with its terms. Each Lender hereby represents, warrants and covenants to the Borrower that:Īuthorization. Representations, Warranties and Covenants. The obligations evidenced by the Bridge shall be secured pursuant to the form of a Security Agreement in substantially the form attached hereto as Exhibit A (the Security Agreement). The Lenders hereby agree to loan to the Borrower, the amount set forth on Schedule I attached hereto through a Bridge Loan (the Bridge) as evidenced by the issuance of a Subordinated Promissory Note dated as of even date herewith (the Note), in a financing by the Borrower (the Bridge Financing). By this BRIDGE LOAN AGREEMENT dated as of (this Agreement), the undersigned (the Lenders) and Smarte Solutions, Inc., a Delaware corporation (the Borrower), hereby agree as follows: wiki-commons:Special:FilePath/EricaCerraCCJuly09.yago:Wikicat21st-centur圜anadianActresses Cerra played the comedic-foil part with an admirably straight face one that’s since remained familiar in both movies and on TV, with a main role in The CW’s The 100 as AI creator Becca (as well.yago:WikicatCanadianPeopleOfItalianDescent.Cerra at the 2009 San Diego Comic-Con (en).Vancouver, British Columbia, Canada (en).dbr:Percy_Jackson_&_the_Olympians:_The_Lightning_Thief.dbr:Battlestar_Galactica_(2004_TV_series). ![]() wiki-commons:Special:FilePath/EricaCerraCCJuly09.jpg?width=300.w serialach Eureka, The 100 i Nie z tego świata. 31 października 1979 w Vancouver) – kanadyjska aktorka, która wystąpiła m.in. Erica Cerra (Vancouver, 31 ottobre 1979) è un'attrice canadese.After a hiatus from acting during her teen years, she restarted her career. 에리카 세라(Erica Cerra, 1979년 10월 31일 ~ )는 캐나다의 배우이다. A native of Vancouver, British Columbia, Erica Cerra began performing as a child.Wiki, Bio, Family, Siblings, Childhood & Education Erica Cerra, who was born on October 31, 1979, will be 43 years old in 2022. She had a breakthrough in her career when she was cast as Deputy Jo Lupo in Eureka. ![]()
![]() Launch Any Video Converter (AVC), and add your media file into AVC.If you don't require Video Encoding or Audio Description for you video, you can submit a proxy file, like an audio version (like MP3), or some other compressed video or audio format. Text Tutorial Converting to the MP3 format: You can download and install Any Video Converter from their website. Any Video Converter comes in both PC and Mac versions, and it's free. This article shows how to use Any Video Converter to transcode your files into a different format. Hopefully, you can have a better understanding of their pros and cons and decide which one to choose by referring to the chart.CaptionSync accepts a variety of media files for Closed Captioning. In the following, it’s the comparison between ClipConverter Online Video Downloader and IOTransfer. ![]() The downloaded video somehow gets targeted as malware and stopped by the firewall on your PC. The high-quality video download can take much time.ģ. Sometimes, ClipConverter doesn’t recognize the YouTube video’s link you offer and a warning “Unable to get video info from YouTube” pops up when video analysis is going on.Ģ. However, there are still some defects or errors you may encounter when using it.ġ. Then, follow the onscreen guide and the YouTube video will be immediately downloaded in MP4.ĬlicpConverter is an efficient and simple online YouTube downloader. Preset MP4 as the video’s output format and click on “Start”. 1080P 60FPS performs best although it generates a larger size.ģ. When the URL analysis is accomplished, you will be prompted to choose the video’s resolution and frame rate. Go to ClipConverter, paste the video link onto the given field and click on “Continue” to launch the URL analysis.Ģ. YouTube MP4 Conversion with An Online Converterīesides a YouTube to MP4 converter of the desktop version, there are still many online YouTube downloader MP4 programs you can find on Google. Tips: Over 20 video & audio formats are supported for conversion. Choose MP4 in the dropdown list of “Output Format:”, preset an output folder for the converted video, and lastly tick off the tiny box before “Automatically transfer the converted video into your iOS device”. Then, click on “+Add Files” and select the downloaded YouTube video from the folder you previously set. Step 3 YouTube Converter MP4 - Change the Downloaded Video to MP4Īfter the video download gets finished, click on “Converter” in the list on the left. Step 2 Download the YouTube Video to Your PCĬlick on “VIDEOS” at the top of the interface, copy and paste the link to your desired YouTube video onto the blank filed beside “URL:”, preset a download path in “Download Location” and then click on “Download” to get started. Tick them all, and click on "Transfer to PC" to back them all up from your iPhone to PC On the main interface, you can see 4 tablets respectively Photos, Music, Videos and Contacts. If the notification “Trust This Computer” pops up, tap on “Trust” on the phone’s screen. if you want to save the YouTube video in MP4 on your iPhone, connect the device to PC and wait until it’s recognized. Step 1 Preparation before the YouTube MP4 Conversion ![]() Moreover, if you are an iPhone user, you can directly transfer the YouTube video into your iPhone within 1 click! Download Any YouTube Videos to MP4 within 3 Steps ![]() Fan can also be swapped or customized.Ĭompatible with current and future Intel and AMD sockets. Intelligent wiring system and sleeved tubing makes this one sleek cooler without the messy wires.Ĭopper base provides maximum heat transfer.īuilt in 240mm radiator and 2x 120mm fans help dissipate the heat keeping the CPU as cool as possible. No filling, no custom tubing, no maintenance. EVGA 0 0 90.0800 add-to-cart low-stock EVGA Black Intel/AMD AMD Radeon RX 6800XT Nitro+ 240 (2 x 120mm) 28mm Īll-in-one cooling solution that is completely self-contained. Available in 120mm, 240mm or 280mm radiator, the EVGA CLC allows DIY professionals and overclockers to extract all the potential of their high-end processors. It's compatible with current and future Intel & AMD sockets with the included mounting hardware. It delivers incredible performance, low noise, robust software controls and RGB lighting. The EVGA Closed Loop CPU Cooler (CLC) is an all-in-one, plug-and-play liquid cooling solution that requires no filling, no custom tubing, or no maintenance. ![]() ![]() 20182 EVGA CLC 240 Liquid / Water CPU Cooler, RGB LED Cooling 109.99 109.9900 USD OutOfStock /Water Cooling/AIO (All-In-One) The EVGA Closed Loop CPU Cooler (CLC) is an all-in-one, plug-and-play liquid cooling solution that requires no filling, no custom tubing, or no maintenance. |
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